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Yeup Yoon Selected Research

LK8 peptide

6/2014Antiangiogenic Therapy with Human Apolipoprotein(a) Kringle V and Paclitaxel in a Human Ovarian Cancer Mouse Model.
6/2013Immunoglobulin Fc domain fusion to apolipoprotein(a) kringle V significantly prolongs plasma half-life without affecting its anti-angiogenic activity.
8/2012Repeated intravenous infusion of human apolipoprotein(a) kringle V is associated with reversible dose-dependent acute tubulointerstitial nephritis without affecting glomerular filtration function.
6/2012Human apolipoprotein(a) kringle V inhibits ischemia-induced retinal neovascularization via suppression of fibronectin-mediated angiogenesis.
4/2012Targeted antivascular therapy with the apolipoprotein(a) kringle V, rhLK8, inhibits the growth and metastasis of human prostate cancer in an orthotopic nude mouse model.

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Yeup Yoon Research Topics

Disease

20Neoplasms (Cancer)
06/2021 - 08/2003
8Neoplasm Metastasis (Metastasis)
10/2020 - 10/2004
3Carcinoma (Carcinomatosis)
06/2014 - 01/2005
3Hepatocellular Carcinoma (Hepatoma)
11/2011 - 05/2006
2Glioma (Gliomas)
10/2018 - 09/2015
2Colorectal Neoplasms (Colorectal Cancer)
02/2016 - 10/2004
2Glioblastoma (Glioblastoma Multiforme)
01/2016 - 12/2015
2Influenza in Birds (Avian Flu)
08/2014 - 05/2009
2Infections
08/2014 - 01/2012
2Human Influenza (Influenza)
08/2014 - 01/2012
2Colonic Neoplasms (Colon Cancer)
05/2006 - 01/2005
1Hematologic Neoplasms (Hematological Malignancy)
10/2018
1Vaccinia
08/2014
1Ovarian Neoplasms (Ovarian Cancer)
06/2014
1Ascites
06/2014
1Acute Tubulointerstitial Nephritis
08/2012
1Vitreous Hemorrhage
06/2012
1Retinal Neovascularization
06/2012
1Diabetic Retinopathy (Retinopathy, Diabetic)
06/2012
1Ischemia
06/2012
1Retinal Detachment (Retinal Detachments)
06/2012
1Prostatic Neoplasms (Prostate Cancer)
04/2012
1Lymphatic Metastasis
04/2012
1Hypersensitivity (Allergy)
12/2009
1Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
12/2009
1Autoimmune Diseases (Autoimmune Disease)
12/2009

Drug/Important Bio-Agent (IBA)

5LK8 peptideIBA
06/2014 - 04/2012
4Therapeutic UsesIBA
01/2018 - 04/2012
4Apoprotein(a) (Apolipoprotein (a))IBA
05/2006 - 08/2003
3Proteins (Proteins, Gene)FDA Link
09/2017 - 01/2012
2Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
10/2020 - 01/2014
2Pharmaceutical PreparationsIBA
10/2020 - 01/2014
2Semaphorin-3AIBA
07/2018 - 01/2018
2Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
12/2017 - 09/2017
2CytokinesIBA
08/2014 - 01/2012
2Influenza Vaccines (Influenza Vaccine)FDA Link
08/2014 - 01/2012
2VaccinesIBA
08/2014 - 05/2009
2Paclitaxel (Taxol)FDA LinkGeneric
06/2014 - 04/2012
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2014 - 08/2003
2Lipocalin-2IBA
02/2011 - 05/2006
2Apolipoproteins AIBA
05/2006 - 08/2003
2Complementary DNA (cDNA)IBA
01/2005 - 10/2004
1SolutionsIBA
06/2021
1N- (((6- biotinoyl)amino)hexanoyl)- 1,2- dihexadecanoyl- sn- glycero- 3- phosphoethanolamineIBA
06/2021
1StreptavidinIBA
06/2021
1pyrrolo(2,1-c)(1,4)benzodiazepineIBA
10/2020
1Immunoconjugates (Immunoconjugate)IBA
10/2020
1ibrutinibIBA
10/2018
1Proto-Oncogene Proteins c-metIBA
09/2017
1Monoclonal AntibodiesIBA
02/2016
1Cetuximab (Erbitux)FDA Link
02/2016
1LigandsIBA
02/2016
1GC1118IBA
02/2016
1Pimozide (Orap)FDA Link
01/2016
1Small Interfering RNA (siRNA)IBA
01/2016
1Temozolomide (Temodar)FDA LinkGeneric
09/2015
1EpitopesIBA
08/2014
1taxaneIBA
06/2014
1Neutralizing AntibodiesIBA
01/2014
1Biomarkers (Surrogate Marker)IBA
10/2013
1Angiogenesis InhibitorsIBA
06/2013
1NitrogenIBA
08/2012
1CreatinineIBA
08/2012
1TinIBA
08/2012
1Urea (Carbamide)FDA LinkGeneric
08/2012
1Fibronectins (Fibronectin)IBA
06/2012
1AndrogensIBA
04/2012
1Immunoglobulin A (IgA)IBA
01/2012
1Immunoglobulin G (IgG)IBA
01/2012
1FlagellinIBA
01/2012
1Interleukin-8 (Interleukin 8)IBA
11/2011
1Bovine Serum AlbuminIBA
12/2009
11,4-diphenyl-2-mercaptoimidazoleIBA
12/2009
1Environmental BiomarkersIBA
05/2009
1matrigelIBA
05/2006
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
08/2003
1angiogeninIBA
08/2003

Therapy/Procedure

11Therapeutics
10/2018 - 10/2004
2Drug Therapy (Chemotherapy)
06/2014 - 04/2012
1Intravenous Infusions
08/2012
1Traction
06/2012
1Intranasal Administration
01/2012
1Oral Administration
12/2009
1Aftercare (After-Treatment)
05/2006